Human Cytomegalovirus UL18 Prevents Priming of MHC-E– and MHC-II–Restricted CD8⁺ T Cells

To determine whether human cytomegalovirus (HCMV) encoded additional, nonconserved inhibitors of unconventional T cell priming, investigators inserted 41 HCMV-specific open reading frames into a chemokine-deficient strain.