Biofunctionalized Gelatin Hydrogels Support Development and Maturation of iPSC-Derived Cortical Organoids

The authors compared Matrigel, a commercially available matrix, to a neural cadherin peptide-functionalized gelatin methacryloyl hydrogel (GelMA-Cad) for culturing cortical neural organoids. They showcased the technical utility of GelMA-Cad as a simple and defined hydrogel alternative to Matrigel for neural organoid culture.