The Dichotomous Roles of Microbial-Modified Bile Acids 7-Oxo-DCA and isoDCA in Intestinal Tumorigenesis

By
Noshin Noorjahan
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Researchers found that although high-fat diet treatment in mice elevated both 7-oxo-deoxycholic acid (7-oxo-DCA) and isoDCA levels, during intestinal tumorigenesis, 7-oxo-DCA levels increased while isoDCA levels decreased.
[Proceedings of The National Academy of Sciences of The United States of America]
Abstract