PARP4 Deficiency Enhances Sensitivity to ATM Inhibitor by Impairing DNA Damage Repair in Melanoma

0
99
Scientists revealed that poly (ADP-ribose) polymerase 4 (PARP4) played a role in double-strand break repair by regulating the non-homologous end joining pathway through its involvement in Ku80 mono-ADP-ribosylation.
[Cell Death Discovery]
Full Article