NewslettersIntestinal Cell News SENP1-Mediated deSUMOylation of YBX1 Promotes Colorectal Cancer Development through the SENP1-YBX1-AKT Signaling Axis By Jamie Kang - February 28, 2025 0 60 Investigators revealed SUMO-specific protease 1 (SENP1)-mediated YBX1 protein deSUMOylation promotes colorectal cancer progression through the activation of AKT phosphorylation signaling. [Oncogene] Full Article