hucMSCs Alleviate LPS-Induced Endothelial Glycocalyx Damage by Secreting Cxcl12 to Activate CXCR4

Researchers discovered that human umbilical cord MSCs alleviate lipopolysaccharide-induced glycocalyx damage in pulmonary vascular endothelial cells by secreting Cxcl12, which activates the downstream receptor CXCR4, providing a therapeutic effect for acute respiratory distress syndrome.