BMSCs Regulate RGS3 Expression in Ovarian Stromal Cells to Improve Ovarian Stromal Fibrosis and Angiogenic Microenvironment in Cyclophosphamide-Induced Premature Ovarian Failure

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Researchers explored the effects of bone marrow derived MSCs on ovarian stromal cells in a premature ovarian failure (POF) modelIn vivo experiments revealed that cyclophosphamide-induced premature ovarian failure rats exhibited irregular estrous cycles and increased deposition of interstitial collagen fibers.
[Stem Cell Research & Therapy]
Abstract