NOD2 Drives Regenerative Fetal-Like Reprogramming in the Intestinal Epithelium

Using irradiation injury as a model for small intestinal epithelium injury and repair, scientists found that the intestinal microbiota accelerated epithelial restitution by amplifying a repair-associated inflammatory response that promoted the emergence of fetal-like intestinal epithelial cells, marked by Ly6a and Clu.