SAC Regulates Glutathione Metabolism via the Keap1/Nrf2/GPX4 Signaling Pathway to Inhibit Ferroptosis and Alleviate Ulcerative Colitis

Scientists investigated the molecular mechanism by which sulfurized garlic (SAC) inhibits ferroptosis through targeting Keap1/Nrf2/GPX4 signaling pathway, thereby restoring intestinal epithelial cell barrier function and alleviating ulcerative colitis.