Long Isoforms of the COPD Risk Gene FAM13A Orchestrate Human Lung Epithelial Development

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Investigators demonstrated that the FAM13A long isoform is critical to patterning NKX2-1 + lung progenitor cells through dysregulating Wnt/β-catenin signaling during early stages of development in vitro.
[American Journal of Respiratory Cell and Molecular Biology]
Abstract