Single-Cell Map of the Healthy Human Immune System across the Lifespan Reveals Unique Infant Immune Signatures

Scientists profiled PBMCs from 167 healthy individuals, infants, children, adolescents, young adults, middle‑aged, older adults and oldest old using scRNA‑seq and snATAC‑seq. They provide insight into human immune system dynamics across the human lifespan, emphasizing unique features of the infant immune system.