SPP1 Macrophages Facilitate the Differentiation and Maturation of Regulatory T Cells in Tumor-Draining Lymph Nodes of Colorectal Cancer

By
Emily Salmini
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SPP1+ macrophages established an immunosuppressive niche in colorectal cancer tumor-draining lymph nodes by promoting CD137+ Treg maturation via the SPP1-CD44-NF-κB1 axis.
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Abstract