ALDH3A2-Mediated Fatty Acid Synthesis Induces Ferroptosis and AML Drug Resistance

Researchers elucidated the expression profile of aldehyde dehydrogenase 3 family member A2 (ALDH3A2) in real-world AML patients and its impact on the efficacy of chemotherapy and explored the effect of inhibiting ALDH3A2 activity or expression on enhancing the sensitivity to chemotherapy.