Endosteal Integrin-α8 Mesenchymal Stem Cells Maintain Hematopoietic Stem Cell Function via Extracellular Matrix-Mediated Interactions

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Scientists identified a distinct subset of MSCs expressing integrin α8 within the bone marrow endosteum. These cells exhibited distinct MSC properties and higher hematopoietic supportive activity than other MSC subsets.
[Nature Communications]
Abstract