PP2Acα Regulates the Hippo-YAP Signaling Axis to Promote Cardiac Regeneration and Alleviate Myocardial Infarction

The authors showed that protein phosphatase 2A (PP2A)cα promotes cardiomyocyte proliferation and heart regeneration by activating Hippo–YAP signaling, revealing a potential therapeutic target for cardiac repair after myocardial infarction.