Stanniocalcin 1 Contributes to Glioma Stem Cells Phenotypic Plasticity through NOTCH1/STAT3/GFPT2 Axis

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Investigators revealed that stanniocalcin 1 (STC1) is a key regulator of GSC phenotypic plasticity and aggressiveness through the NOTCH1/STAT3/GFPT2/O-GlcNAcylation pathway.
[Oncogenesis]
Abstract