Glycolytic Enolase 1-Induced H4K12 Lactylation Activates Quiescent Breast Cancer Stem-Like Cells in Triple-Negative Breast Cancer

Researchers developed a dual-reporter system combining NANOG-EGFP and H2B-mCherry pulse-chase labeling to separately identify quiescent or extremely slow-cycling breast cancer stem-like cells and active BCSCs in vitro and in vivo.