3D imaging

[Biosensors & Bioelectronics] Scientists reported Fourier light-field microscopy using a hybrid point-spread function for fast, volumetric, and high-resolution imaging of entire organoids.

[Development] Scientists presented a light-sheet fluorescence microscopy approach to image the pancreas in 3D and map tissue interactions at key time points in the mouse embryo.

[Hepatology] Researchers showed that intrahepatic duct cells regenerated upon resumption of Jag/Notch signaling, from multipotent progenitors originating from an Fgf-dependent extrahepatic stem cell niche.

[Communications Biology] Scientists demonstrated the utility of the approach by providing volumetric data and 3D distribution of hundreds of thousands of islets of Langerhans within the human pancreas.

[Cell Stem Cell] Lineage tracing using the Neurogenin3 (Ngn3)-CreERT line identified ductal cells expressing the endocrine master transcription factor Ngn3 that were positive for the δ cell marker somatostatin and occasionally co-expressed insulin.

[iScience] Investigators applied a dual 3D imaging and spectroscopic technique, based on scanned electron probes, to measure Fe3+ in ex vivo human erythropoietic stem cells.