AKT

[Scientific Reports] Using in silico and in vitro techniques, investigators demonstrated heterogeneous expression of CD97, a leukocyte adhesion marker, in human glioblastoma.

[Signal Transduction and Targeted Therapy] Scientists identified two 4q12 long noncoding RNAs LCETRL3 and LCETRL4 which could significantly dimmish EGFR-TKIs efficiency.

[Journal of Cellular Physiology] The authors found a highly significant correlation between pregnancy-associated plasma protein (PAPP)-A expression in IPF lung tissue and disease severity as measured by various pulmonary and physical function tests.

[Journal of Proteomics] The authors studied the proteome profiled of canine native and decellularized placenta to characterize the proteome related to maintenance of a microenvironment and structure suitable for tissue engineering applications.

[Stem Cell Reviews and Reports] Researchers revealed that treatment with the human umbilical cord mesenchymal stromal cells significantly increased the proportion of activated primordial follicles in mouse ovaries both in vitro and in vivo.

[Molecular Cancer therapeutics] Scientists investigated the response of PTEN wild-type prostate cancer cell lines to the dual PI3K/mTOR inhibitor DS-7423 alone or in combination with HER2 inhibitors or mGluR1 inhibitors.