Alzheimer's disease

[International Journal of Urology] Further study into the “Gut–Prostate Axis” would help in the discovery of new strategies for the prevention, screening, and treatment of prostate cancer.

[Pharmacology & Therapeutics] Investigators summarize the latest studies on the role that altered neuronal autophagy plays in brain health and these pathological conditions, and how this knowledge can be leveraged for the development of novel therapeutics against them.

[FASEB Journal] Checkpoint kinase 1 (ChK1)-mediated Cancerous Inhibitor of PP2A (CIP2A) overexpression drove inhibition of PP2A and activated STAT3, then led to reactive astrogliosis and neurodegeneration in vitro.

[Biophysical Journal] Investigators found that AGA(C8R)-HNG17 confered protection against necrosis in neuronal cell lines PC-12 and NSC-34, where necrosis was induced in a glucose-free medium by either chemohypoxia or by a shift from apoptosis to necrosis.

[Histology and Histopathology] Investigators review the levels of S1P in those vascular and vascular-related diseases. Plasma S1P levels were reduced in various inflammation-related diseases such as atherosclerosis and sepsis, but were increased in other diseases including type 2 diabetes, neurodegeneration, and cerebrovascular damage.

[Journal of Applied Toxicology] The authors review currently available information on lead (Pb)-mediated alterations in the fetal epigenome is summarized.