B cells

[Journal of Immunology] The authors provided a comprehensive molecular and functional comparison of B cell subsets from umbilical cord blood and adult peripheral blood.

[Life Science Alliance] Using a human umbilical cord blood xenotransplantation model, we show here that co-transplanted allogeneic CD4+ iNKT cells interact with monocytes and T cells in the graft to coordinate pro-hematopoietic and immunoregulatory pathways.

[Genome Medicine] The authors explored the set of computationally predicted SARS-CoV-2 HLA-I and HLA-II ligands, examining protein source, concurrent human/murine coverage, and population coverage.

[Bristol Myers Squibb] Bristol Myers Squibb announced positive results from TRANSFORM, a Phase III study evaluating Breyanzi as a second-line treatment in adults with relapsed or refractory large B-cell lymphoma compared to salvage therapy followed by high-dose chemotherapy and hematopoietic stem cell transplant.

[Science Immunology] Researchers showed that the SARS-CoV-2 envelope protein alone is able to cause acute respiratory distress syndrome-like damages in vitro and in vivo.

[Cell Reports] Scientists investigated SARS-CoV-2 spike-specific memory B cells and their dependence on CD4+ T cell help in different settings of COVID-19.