Using a human umbilical cord blood xenotransplantation model, we show here that co-transplanted allogeneic CD4+ iNKT cells interact with monocytes and T cells in the graft to coordinate pro-hematopoietic and immunoregulatory pathways.
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Hess, N. J., Bharadwaj, N. S., Bobeck, E. A., McDougal, C. E., Ma, S., Sauer, J.-D., Hudson, A. W., & Gumperz, J. E. (2021). iNKT cells coordinate immune pathways to enable engraftment in nonconditioned hosts. Life Science Alliance, 4(7). https://doi.org/10.26508/lsa.202000999 Cite