Researchers analyzed the molecular determinants of monocytic and macrophagic commitment by profiling the EGR1 transcription factor. EGR1 is essential for monopoiesis and binds enhancers that regulate monocytic developmental genes such as CSF1R.
[Science Advances]
EGR1 is a gatekeeper of inflammatory enhancers in human macrophages | Science Advances. (n.d.). Retrieved January 18, 2021, from https://advances.sciencemag.org/content/7/3/eaaz8836 Cite
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