Scientists established that nutrient uptake and signaling are key determinants of T cell fate and shape the quantity and quality of memory T cell responses.
[Cell]
Huang, H., Zhou, P., Wei, J., Long, L., Shi, H., Dhungana, Y., Chapman, N. M., Fu, G., Saravia, J., Raynor, J. L., Liu, S., Palacios, G., Wang, Y.-D., Qian, C., Yu, J., & Chi, H. (2021). In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions. Cell, 0(0). https://doi.org/10.1016/j.cell.2021.02.021 Cite
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