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Bax

Dual Akt and Bcl-2 Inhibition Induces Cell-Type Specific Modulation of Apoptotic and Autophagic Signaling in Castration Resistant Prostate Cancer Cell Lines

[Molecular Biology Reports] The authors elucidated the modulation patterns between apoptosis and autophagy following dual inhibition by Akt inhibitor erufosine and Bcl-2 inhibitor ABT-737 in castration-resistant prostate cancer cell lines, PC-3 (Bax+) and DU-145 (Bax−).

Inhibition of JAK2/STAT3 Signaling Pathway by Panaxadiol Limits the Progression of Pancreatic Cancer

[Aging-Us] Investigators found panaxadiol significantly inhibited proliferation, and induced apoptosis in human pancreatic cancer cell lines PANC-1 and Patu8988 in a dose-dependent manner.

Baxter Announces US Approval and Launch of Ready-to-Use Cardiovascular Medicine Norepinephrine in Premix Formulation

[Baxter International Inc.] Baxter International, Inc. announced the US FDA approval and commercial launch of premix Norepinephrine Bitartrate in 5% Dextrose Injection.

Chlorothalonil Induces the Intestinal Epithelial Barrier Dysfunction in Caco-2 Cell-Based In Vitro Monolayer Model by Activating MAPK Pathway

[Acta Biochimica et Biophysica Sinica] Scientists used Caco-2 cell monolayers as an in vitro model of human intestinal epithelial barrier (IEB) to evaluate the toxicity of chlorothalonil exposure on the structure and function of IEB.

The Anti-Tumor Effect of Induced Pluripotent Stem Cells against Submandibular Gland Carcinoma in Rats Is Achieved via Modulation of the Apoptotic Response and the...

[Molecular and Cellular Biochemistry] The authors investigated the contribution of the Bax, Sirt-1, TGF-β, and MALAT genes and/or their protein expression to the pathogenesis of submandibular carcinogenesis before and after iPSCs treatment.

Atractylenolide III Induces Apoptosis by Regulating the Bax/Bcl-2 Signaling Pathway in Human Colorectal Cancer HCT-116 Cells In Vitro and In Vivo

[Anti-Cancer Drugs] The results showed that atractylenolide III significantly inhibited the cell growth and induce cellular apoptosis in HCT-116 cells in a concentration dependence manner in vitro.

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