EMT

[Cancer Biology & Therapy] Scientists showed that fibroblast growth factor receptor 2 (FGFR2), particularly the IIIb isoform, was highly expressed in non-CSCs.

[Nature Communications] Researchers used single-cell RNA sequencing at key developmental timepoints to interrogate cellular contributions to coronary vessel patterning and maturation.

[Experimental Dermatology] The silencing of long non-coding RNAs (lncRNA) MSC antisense RNA 1 (MSC-AS1) hindered cell proliferation, migration and epithelial-mesenchymal transition in vitro and tumor growth

[Respiratory Research] The authors investigated the role and mechanisms of enhancer of zeste homolog 2 (EZH2) in pulmonary fibrosis in a murine model of LPS-induced acute respiratory distress syndrome (ARDS) and in ex vivo cultured alveolar macrophages and mouse lung epithelial cell line by using 3-deazaneplanocin and EZH2 the small interfering RNA.

[Journal of Gene Medicine] Circular RNAs (circRNAs) are crucial regulators in tumor occurrence and progression, and circRNAs are enriched and stable in exosomes. Investigators explored the role and potential mechanism of cancer-derived exosomal circ_0081234 in prostate cancer.

[Molecular Medicine Reports] M2‑like tumor‑associated macrophages (TAMs) accelerated the metastasis and increased the stemness of anaplastic thyroid carcinoma cells, and the underlying mechanism may have been related to the section of insulin‑like growth factor by M2‑like TAMs, which activated the IR‑A/IGF1R‑mediated PI3K/AKT/mTOR signaling pathway.