HIV

[Communications Biology] Scientists showed how people living with HIV-1 (PLWH) who naturally control the virus had a reduced proportion of CD4+CCR6+ and CD8+CCR6+ cells compared to PLWH on suppressive antiretroviral therapy and HIV-1 negative controls.

[Neurotherapeutics] Individuals with HIV-associated amyotrophic lateral sclerosis (ALS) show a remarkable response to antiretroviral therapy; however, antiretroviral trials in ALS down-regulate HML-2 without ameliorating the disease.

[Nature Communications] Scientists performed comprehensive immunoprofiling of the humoral response to HIV-1 in long-term post-treatment controllers.

[Nature Medicine] Investigators administered a recombinant bicistronic adeno-associated virus (AAV8) vector coding for both the light and heavy chains of the potent broadly neutralizing HIV-1 antibody VRC07 to eight adults living with HIV.

[Cell Reports] Investigators showed that HIV-1 cell-to-cell spread permited efficient, productive infection of resting memory T cells without prior activation.

[World Health Organization] The WHO Strategic Advisory Group of Experts on Immunization concluded that a single-dose HPV vaccine delivers solid protection against HPV, the virus that causes cervical cancer, that is comparable to two-dose schedules.