HIV

[Nature Communications] Scientists performed comprehensive immunoprofiling of the humoral response to HIV-1 in long-term post-treatment controllers.

[Nature Medicine] Investigators administered a recombinant bicistronic adeno-associated virus (AAV8) vector coding for both the light and heavy chains of the potent broadly neutralizing HIV-1 antibody VRC07 to eight adults living with HIV.

[Cell Reports] Investigators showed that HIV-1 cell-to-cell spread permited efficient, productive infection of resting memory T cells without prior activation.

[World Health Organization] The WHO Strategic Advisory Group of Experts on Immunization concluded that a single-dose HPV vaccine delivers solid protection against HPV, the virus that causes cervical cancer, that is comparable to two-dose schedules.

[Clinical infectious Diseases] Researchers investigated SARS-CoV-2 vaccine immunogenicity in PLWH according to current CD4 T-cell count.

[Stem Cell Reports] Scientists report successful targeting of the CCR5 locus in iPSCs generated from T cells or fibroblasts from Mauritian cynomolgus macaques, using CRISPR-Cas9 technology.