HUVECs

[Stem Cell Research & Therapy] Investigators examined whether by phosphatase regenerating liver-1, overexpressed placental-derived-MSCs, could maximize the angiogenic effects in ovarian tissues injured of a rat model with partial ovariectomy.

[Bioengineered] Scientists found that in oxidized low-density lipoprotein-treated HUVECs, the increased production of total cholesterol, free cholesterol, and pro-inflammatory cytokines were observed, reversed by 10 μM and 25 μM Nintedanib.

[Journal of Ethnopharmacology] Shuxuetong injection promoted angiogenesis and improved function recovery in hindlimb ischemia mice by regulation of VEGF-A/platelet-derived growth factor.

[Genomics] Scientists explored the mechanism of human umbilical cord mesenchymal stem cells-derived extracellular vesicles loaded with miR-223 on myocardial infarction. Inflammation, cell biological functions, and fibrosis in vitro were measured.

[iScience] Scientists demonstrated that treatment with exosomes from high glucose-pretreated immortalized human epidermal cells could delay the wound healing process in diabetic mice.

[Colloids and Surfaces B-Biointerfaces] Rat bone marrow derived MSCs and human umbilical vein endothelial cells were co-cultured onto scaffolds fabricated by the authors to enhance vascularization for bone tissue regeneration.