Tag results:

IL-6

Caspase-9b Drives Cellular Transformation, Lung Inflammation, and Lung Tumorigenesis

[Molecular Cancer Research] A transgenic mouse model expressing human Caspase-9b in the lung pneumocytes developed inflammatory lung lesions, which correlated with enhanced activation of the NF-κB pathway and increased influx of immunosuppressive MDSCs in contrast to wild-type mice.

Nrf2 and NF-κB/NLRP3 Inflammasome Pathways Are Involved in Prototheca bovis Infections of Mouse Mammary Gland Tissue and Mammary Epithelial Cells

[Free Radical Biology and Medicine] Investigators characterized how Prototheca bovis induced inflammatory responses in mouse mammary gland tissue and mammary epithelial cells.

Targeted P2X7/NLRP3 Signaling Pathway against Inflammation, Apoptosis, and Pyroptosis of Retinal Endothelial Cells in Diabetic Retinopathy

[Cell Death & Disease] Scientists evaluated the anti-inflammatory effects and potential mechanisms of action of 3TC in vitro in retinal microvascular endothelial cells treated with high-glucose and lipopolysaccharide.

Liver-Specific Overexpression of Gab2 Accelerates Hepatocellular Carcinoma Progression by Activating Immunosuppression of Myeloid-Derived Suppressor Cells

[Oncogene] Liver-specific overexpression of GRB2-associated-binding protein 2 (Gab2) mice accelerated hepatoma progression possibly through activating IL-6-initiated the activation of myeloid-derived suppressor cells.

Liver-Specific Overexpression of Gab2 Accelerates Hepatocellular Carcinoma Progression by Activating Immunosuppression of Myeloid-Derived Suppressor Cells

[Oncogene] Liver-specific overexpression of GRB2-associated-binding protein 2 (Gab2) mice accelerated hepatoma progression possibly through activating IL-6-initiated the activation of myeloid-derived suppressor cells.

Nigella sativa L. as Immunomodulator and Preventive Effect on Renal Tissue Damage of Lupus Mice Induced by Pristane

[Heliyon] The authors indicated that Nigella sativa L. had an immunomodulatory effect and could prevent kidney injury pristane induced Lupus-treated mice.

Popular