M cells

[Life Sciences] The authors demonstrated that the miRNA miR-142-3p directly targeted the 3′ untranslated region of HMGA2, which encoded an onco-embryonic protein that was overexpressed in most cancers, including breast cancer.

[Scientific Reports] Peptides from milk proteins is gaining popularity in various therapeutics including human cancer. Researchers investigated the anti-cancerous and anti-inflammatory properties of camel whey protein hydrolysates

[Scientific Reports] While cyclin-dependent kinase 1 (CDK1) phosphorylation is a well-described consequence of temozolomide (TMZ) treatment, researchers found that TMZ also robustly induced CDK1 expression.

[Cell Death & Disease] Investigators describe results with a new anti-cancer small molecule, WEHI-7326, which caused cell cycle arrest in G2/M, cell death in vitro, and displayed efficacious anti-tumor activity in vivo.

[Cell Communication and Signaling] Scientists summarize the signaling pathways contributing to intestinal cell fates and homeostasis functions, focusing on intestinal stem cell proliferation, cell junction formation, remodeling, hypoxia, the impact of intestinal microbiota, the immune system, inflammation, and metabolism.

[Scientific Reports] Cell division cycle 6 (Cdc6)-depleted pancreatic cancer cells significantly inhibited cell proliferation and colony formation, delayed G2/M cell cycle progression, and increased expression of p-histone H3 and cyclin A2 levels.