MYC

[Cell Death & Disease] Researchers explored a prognostic model for the estimation of tumor-associated mortality in gastric cancer (GC) patients and revealed the RNA-binding protein RBMS1 as a candidate promoter gene for GC metastasis by analyzing GOBO and oncomine high-throughput sequencing datasets for 408 GC patients.

[Life Science Alliance] The authors sought to alter transcriptional programs by enforcing expression of the catalytic domain of the methylcytosine dioxygenase TET2 in breast cancer cells.

[Anti-Cancer Drugs] Scientists investigate the effect of Ubiquitin-specific protease 1 (USP1) depletion with chemotherapeutant doxorubicin on the hepatocellular carcinoma cells.

[Oncogene] Researchers identified and isolated chemoradiotherapy-resistant cancer stem cells in quiescent state with high capacity of tumor-initiation and tumorsphere formation from three types of breast tumors in mice.

[Neuro-Oncology] The authors established the relevance of interclonal cross-talk between MYC-driven and non-MYC-driven medulloblastoma cells.

[Molecular Cancer] miR-346 could be particularly effective as a therapeutic in the context of decreased NORAD observed in advanced prostate cancer, and in transcriptionally-hyperactive cancer cells.