NSCLC

[Journal of Biochemistry] Using ectopic plasmid incorporation and siRNA assays, investigators analyzed the circRPPH1-mediated regulation of cell proliferation, migration, and invasion in NSCLC cell lines, using CCK-8, colony forming, scratch wound, and transwell assays, respectively.

[Cancer Biology & Medicine] Scientists investigated the radiosensitizing efficacy of the poly-ADP-ribose polymerase (PARP) inhibitor, olaparib, and the bloom syndrome protein (BLM) helicase inhibitor, ML216, in NSCLC cells.

[Biosplice Therapeutics, Inc.] Biosplice Therapeutics, Inc. announced the dosing of the first subject in a Phase Ib, open-label, multicenter, dose-escalation, dose expansion clinical trial of cirtuvivint in subjects with advanced solid tumors.

[Nature] Researchers identified a novel fusion transcript of CLIP1 and LTK using whole-transcriptome sequencing in a multi-institutional genome screening platform

[Experimental Cell Research] Researchers investigated the effects of Ad-apoptin on glycolysis, migration and invasion of non-small cell lung cancer.

[Naunyn-Schmiedebergs Archives of Pharmacology] The research achievements in recent years on the regulating mechanism of ferroptosis and its effect on the occurrence and the therapy of lung cancer are reviewed.