Nanog

[Journal of Cellular Biochemistry] Scientists revealed the differences in methionine metabolism of bone marrow (BM)-mesenchymal stem cells (MSCs), umbilical cord blood-MSCs, and cancer stem cells, which reflect different metabolic profiles and developmental stages of stem cells.

[Cancer Letters] Scientists found that progestin resistance of endometrial CSCs could be improved or reversed by using in vitro fertilization (IVF)-generated embryonic sac-derived fluid containing the embryonic microenvironment.

[Cell Biology and Toxicology] Researchers investigated its expression profile in neuroblastoma (NB), its association with NB clinical outcomes, and its influence in the regulation of cancer stem cells’ (CSCs) stemness maintenance.

[Nature Communications] ARID1B-BAF regulated exit from pluripotency and lineage commitment by attenuating thousands of enhancers and genes of the NANOG and SOX2 networks. In iPSCs, these enhancers were maintained active by ARID1A-containing BAF.

[Stem Cell Reviews and Reports] Scientists investigated very small embryonic-like cells (VSELs)-like cells in terms of their pluripotency phenotype and tri-lineage differentiation potential.

[Oncogene] Using several in vitro and in vivo models lacking C1GALT1 expression, investigators identified the role of aberrant O-glycosylation in stemness properties and aggressive pancreatic cancer metastasis.