Oct4

[Cancer Letters] Scientists found that progestin resistance of endometrial CSCs could be improved or reversed by using in vitro fertilization (IVF)-generated embryonic sac-derived fluid containing the embryonic microenvironment.

[Cancer Science] Researchers demonstrated that high expression of karyopherin α2 was positively correlated with radioresistance and CSC properties in lung adenocarcinoma cells.

[Journal of Immunology Research] Scientists explored the differentially expressed miRNAs related to tumor cell-derived extracellular vesciles (EVs) and the mechanism by which EVs regulated hepatoblastoma progression.

[Science Advances] The authors reported the ATP-binding cassette subfamily F member 1 (ABCF1) as a coactivator for OCT4/SOX2 critical for stem cell self-renewal.

[Journal of Translational Medicine] The expression of miR-3065-3p in colorectal cancer and the association of miR-3065-3p expression with prognosis of patients with colorectal cancer were analyzed using TCGA dataset or clinical cases.

[Stem Cell Research] Researchers employed non-homologous recombination and generated a mouse ESC line carrying a transgene expressing DNMT1 Y495C mutation in the wild-type background as a model for studying the abnormal neurogenesis due to this mutation.