PDGF

[NPJ Regenerative Medicine] In the type 1 diabetic NOD mouse model, engineered growth factors improved both re-epithelialization and granulation tissue formation.

[Bone Research] The authors found that the multinucleation of osteoclasts was inhibited in SIGLEC-15 conditional knockout mice and mice undergoing Siglec-15 neutralizing antibody treatment.

[Cell Reports] The authors suggested that infiltrative monocytes promoted fibrogenesis in nonalcoholic fatty liver disease via ADA2-mediated autocrine/paracrine signaling culminating in enhanced PDGF-B production.

[Cell Death Discovery] Investigators suggested that miR548ai, a rarely known microRNA, may have provided a molecular target for protection against smooth muscle cell/exosome-induced endothelial cell dysfunction.

[Matrix Biology] Investigators indicated that elevated TGFβ signaling led to an attenuated response to growth factors, which contributed to impaired dermal wound healing in recessive dystrophic epidermolysis bullosa.

[Arteriosclerosis Thrombosis and Vascular Biology] Researchers investigated the role and mechanism of circSOD2 in smooth muscle cell proliferation and neointima formation.