Tag results:
STAT3
Endothelial Cell News
LIF, a Mitogen for Choroidal Endothelial Cells, Protects the Choriocapillaris: Implications for Prevention of Geographic Atrophy
[EMBO Molecular Medicine] Scientists identified leukemia inhibitory factor (LIF) as a mitogen for bovine choroidal endothelial cell (EC), although LIF had been mainly characterized as an EC growth inhibitor and an anti-angiogenic molecule.
Prostate Cell News
The Metastasis Suppressor NDRG1 Directly Regulates Androgen Receptor Signaling in Prostate Cancer
[Journal of Biological Chemistry] Scientists examined for the first time the effect of N-myc-downregulated gene 1 (NDRG1) on androgen receptor expression, activation, and downstream signaling in LNCaP, 22Rv1 and C4-2B prostate cancer cell types.
Pulmonary Cell News
Vitamin E Relieves Chronic Obstructive Pulmonary Disease by Inhibiting COX2-Mediated P-STAT3 Nuclear Translocation through the EGFR/MAPK Signaling Pathway
[Laboratory Investigation] Scientists explored the protective effect of vitamin E on chronic obstructive pulmonary disease and the underlying mechanisms.
Umbilical & Placental Cell News
MiR-455-5p Upregulation in Umbilical Cord Mesenchymal Stem Cells Attenuates Endometrial Injury and Promotes Repair of Damaged Endometrium via Janus Kinase/Signal Transducer and Activator of...
[Bioengineered] Scientists investigated the specific impacts of umbilical cord mesenchymal stem cells overexpressing miR-455-5p in intrauterine adhesions.
Mammary Cell News
The Inhibition of Circular RNA circNOLC1 by Propofol/STAT3 Attenuates Breast Cancer Stem Cells Function via miR-365a-3p/STAT3 Signaling
[Journal of Translational Medicine] Scientists explored the function of circular RNA nucleolar and coiled-body phosphoprotein 1 (circNOLC1) in cancer stem cells of breast cancer and the inhibitory impact of propofol on circNOLC1.
ESC & iPSC News
The Distinct Responsiveness of Cytokeratin 19-Positive Hepatocellular Carcinoma to Regorafenib
[Cell Death & Disease] Regorafenib preferentially increased the growth inhibition and apoptosis of CK19+ cells in vitro, whereas sorafenib, apatinib, and 5-fluorouracil did not.