Sox2

[Molecular Cancer Research] The authors showed that a selective Raf kinase inhibitor protein (RKIP) inducer inhibited tumor growth and promoted schwannoma cell differentiation into mature Schwann cells under NF2-deficient conditions.

[Oncogene] Scientists showed that thyroid hormone receptor β (TRβ) was a newly identified transcription regulator that acted to suppress CSC activity and that TRβ could be considered as a molecular target for therapeutic intervention of anaplastic thyroid cancer cells.

[Small] The authors found that gelatin methacryloyl (GelMA)-nanoclay hybrid hydrogels could induce and enrich colorectal cancer stem cells assisted by three-dimensional bioprinting.

[Cell Death & Disease] Researchers reported that expression of mucin 15 (MUC15) was downregulated in liver tumor-initiating cells, chemoresistance, and recurrent HCC samples.

[Cell Stem Cell] Researchers reported the discovery of human 8-cell (8C)-like cells among naive ESCs, which transcriptionally resembled the 8C human embryo.

[Scientific Reports] Gene knockout studies revealed that SOX2 was an essential factor for the generation of CSCs by HRASV12 in mouse and human fibroblasts.