Tag results:
T cells
Extracellular Matrix News
Pretreatment Tumor Immune Microenvironment Predicts Clinical Response and Prognosis of Muscle-Invasive Bladder Cancer in the Neoadjuvant Chemotherapy Setting
[British Journal of Cancer] Scientists examined the relationship between the tumor microenvironment and the clinical efficacy of neoadjuvant chemotherapy in patients with cT2-4aN0M0 bladder cancer using multiplex fluorescence immunohistochemistry.
Hematopoiesis News
Signal-Transducing Adaptor Protein-1 and -2 in Hematopoiesis and Diseases
[Experimental Hematology] Recent findings have shown the critical roles of signal-transducing adaptor protein (STAP)-2 in B cell progenitor cells in marrow under hematopoietic stress and STAP-1 and -2 in BCR-ABL-transduced leukemogenesis. In this review, the authors focus on the role of STAPs in the bone marrow.
Cell Therapy News
Antigen Multimers: Specific, Sensitive, Precise, and Multifunctional High-Avidity CAR-Staining Reagents
[Matter] Investigators developed tetrameric and dodecameric forms of a multifunctional and extensible category of high-avidity CAR-staining reagents: antigen multimers.
Cell Therapy News
A Novel CD34-Derived Hinge for Rapid and Efficient Detection and Enrichment of CAR T-cells
[Molecular Therapy-Oncolytics] For establishing a novel hinge derived from human CD34, researchers systematically tested CD34 fragments of different lengths, all containing the binding site of the QBend-10 monoclonal antibody, in a FMC63-based CD19 CAR lentiviral construct.
Cell Therapy News
T Lymphocyte-Captured DNA Network for Localized Immunotherapy
[Journal of the American Chemical Society] The authors reported a cell capture DNA network containing polyvalent multimodules for the specific isolation and in situ incubation of T lymphocytes.
Human Immunology News
MicroRNA-29 Specifies Age-Related Differences in the CD8+ T Cell Immune Response
[Cell Reports] Scientists examined the role of miR-29 in neonatal and adult CD8+ T cells, which expressed different amounts of miR-29 only prior to infection and adopt profoundly different fates after immune challenge.