T cells

[Science Translational Medicine] The authors reported the correlates of durability of humoral and cellular immune responses in 20 rhesus macaques immunized with single-shot Ad26.COV2.S and the immunogenicity of a booster shot at eight to ten months following the initial immunization.

[Nature Immunology] Researchers showed that the transcription factor Tcf1 was required in resting central memory CD8+ T cells to generate secondary effector CD8+ T cells and to clear pathogens during recall responses.

[Cell Reports] Investigators found that diminished expression of a model tissue-restricted antigen gene in aged thymic stromal cells correlated with impaired clonal deletion of cognate T cells recognizing an autoantigen involved in atherosclerosis.

[Science Immunology] Researchers investigated how changes to naive CD8+ T cell gene expression depended on the basic leucine zipper ATF-like transcription factor Batf, which was essential for the early phases of the process.

[International Immunopharmacology] Scientists found that C-C motif chemokine ligand 2 (CCL2) recruits monocytes to and decrease CD8+ T cell infiltration in pancreatic tumors.

[International Immunopharmacology] Scientists found that C-C motif chemokine ligand 2 (CCL2) recruits monocytes to and decrease CD8+ T cell infiltration in pancreatic tumors.