T cells

[Journal of Hematology & Oncology] The authors review the mitochondrial characteristics of exhausted T cells and particularly discuss different aspects of mitochondrial metabolism and plasticity.

[Cancer Cell International] The authors indicated a relationship between synaptosome associated protein 25 (SNAP25) expression and prostate cancer, demonstrating that SNAP25 was a potential prognostic biomarker due to its vital role in immune infiltration.

[Cell Genomics] Investigators mapped genetic regulation of gene expression and chromatin activity in regulatory T cells and identified 133 colocalizing loci with immune disease variants.

[Nature Immunology] Researchers developed a genetic-tracing approach, termed the DivisionRecorder, that reported the extent of past proliferation of cell pools in vivo.

[Twist Bioscience Corporation] Twist Bioscience Corporation and MediSix Therapeutics announced a collaboration to discover novel antibodies against five undisclosed targets. Twist will leverage its proprietary Library of Libraries to discover five novel antibodies directed against MediSix’s targets.

[Shenzhen Pregene Biopharma Co. Ltd (Cision US, Inc.)] Shenzhen Pregene Biopharma and CellPoint announced an exclusive license agreement for the development and commercialization of PRG-1801, Pregene's single domain antibody-based anti-BCMA chimeric antigen receptor (CAR) T cell program, for the treatment of hematological indications in Europe and the United States.