acute lung injury

[Scientific Reports] we aim to characterize microvesicles shed from pneumolysin-stimulated alveolar epithelial cells and explore their contribution in mediating crosstalk with neutrophils.

[Science Translational Medicine] Researchers found that pazopanib ameliorated acute lung injury (ALI) manifestations and reduced mortality in mouse ALI models and reduced edema in human lung transplantation recipients.

[Stem Cell Research & Therapy] Intratracheal bleomycin was used to induce acute lung injury in mice, and intratracheal MSCs in a supernatant lyophilized powder was administered as a treatment.

[Journal of Translational Medicine] In vivo, the role of panaxydol (PX) on lipopolysaccharide (LPS)-induced acute lung injury in mice was tested by determination of LPS-induced pulmonary inflammation, pulmonary edema and ferroptosis. In vitro, BEAS-2B cells were used to investigate the molecular mechanisms by which PX functions via determination of inflammation, ferroptosis and their relationship.

[Acta Pharmacologica Sinica] Scientists explored the therapeutic potential of bone marrow-derived mesenchymal stromal cell (BMSC)-derived exosomes against acute lung injury and the underlying mechanisms.

[Arch Biopartners, Inc.] Arch Biopartners, Inc. announced that the Peter Lougheed Center in Calgary, Alberta has joined the Phase II trial of its lead drug LSALT peptide, targeting the prevention of acute lung injury, acute kidney injury, and other complications caused by inflammation in hospitalized patients with moderate to severe cases of COVID-19.