adipocytes

[Cell Death & Disease] Researchers provided evidence that high-mobility group box 2 (HMGB2) deficiency in preadipocytes impeded adipogenesis, while overexpression of HMGB2 increased the potential for adipogenic differentiation.

[Scientific Reports] Investigators developed a human-on-a-chip model composed of human hepatocytes and adipose tissue chambers capable of modeling the metabolic factors that contribute to liver disease development and progression, and evaluation of the therapeutic metformin.

[Nature Reviews Urology] The authors discuss exercise-induced myokines and their effect on prostate cancer.

[FEBS Journal] Scientists provide a detailed overview of the pathways and metabolic routes that can be modulated to halt and redirect their fibro/adipogenic potential while favoring their supportive role in muscle regeneration.

[Cell Death & Disease] Researchers investigated molecular mechanisms underlying circular RNA AFF4-regulated Bone marrow-derived-MSCs osteogenesis.

[Oncogene] Investigators showed that the cholesterol-lowering drugs statins decreased castration-induced bone marrow adiposity in the tumor microenvironment and reduced prostate cancer progression in bone.