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adipose-derived stem cells

FGF2-Primed 3D Spheroids Producing IL-8 Promote Therapeutic Angiogenesis in Murine Hindlimb Ischemia

[npj Regenerative Medicine] Scientists demonstrated that IL-8 was upregulated by the FGF2-mediated priming effect during FECS-Ad formation. Immobilized FGF2 substrate induced stronger IL-8 expression than soluble FGF2 ligands, presumably through the FGFR1/JNK/NF-κB signaling cascade.

Differential Effects of Rat ADSCs Encapsulation in Fibrin Matrix and Combination Delivery of BDNF and Gold Nanoparticles on Peripheral Nerve Regeneration

[BMC Neuroscience] The inner surface of electrospun poly nanofibrous conduit was biofunctionalized with laminin containing brain derived neurotrophic factor (BDNF) and gold nanoparticles in chitosan nanoparticle.

Adipose-Derived Stem Cell Exosomes Promoted Hair Regeneration

[Tissue Engineering and Regenerative Medicine] Adipose-derived stem cells were isolated from 6-week-old C57BL/6 mice. Western blotting was used to detect specific exosome markers.

Multiplexed Targeting of miRNA-210 in Stem Cell-Derived Extracellular Vesicles Promotes Selective Regeneration in Ischemic Hearts

[Experimental and Molecular Medicine] Under hypoxic conditions, the authors observed that ASCmiR-210 inhibited apoptosis by modulating protein tyrosine phosphatase 1B and death-associated protein kinase 1.

BPA and BPA Alternatives BPS, BPAF, and TMBPF, Induce Cytotoxicity and Apoptosis in Rat and Human Stem Cells

[Ecotoxicology and Environmental Safety] The authors used adult female rat adipose-derived stem cells and human mesenchymal stem cells to compare the toxicities and potencies of bisphenol A (BPA) alternatives in vitro.

Adipose-Derived Stem Cells Combined with Platelet-Rich Plasma Enhance Wound Healing in a Rat Model of Full-Thickness Skin Defects

[Stem Cell Research & Therapy] Researchers hypothesized that the combination of adipose-derived stem cells and platelet-rich plasma might achieve optimally efficient diabetic wound healing.

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