Umbilical Cord Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis: an Original Study

67 patients were treated with Wharton’s jelly mesenchymal stem cells. The treated patients were paired with 67 reference patients from the PRO-ACT database which contains patient records from 23 amyotrophic lateral sclerosis clinical studies
[Stem Cell Reviews and Reports]
Barczewska, M., Maksymowicz, S., Zdolińska-Malinowska, I., Siwek, T., & Grudniak, M. (2020). Umbilical Cord Mesenchymal Stem Cells in Amyotrophic Lateral Sclerosis: an Original Study. Stem Cell Reviews and Reports. https://doi.org/10.1007/s12015-020-10016-7 Cite
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Proteomics Analysis of FUS Mutant Human Motoneurons Reveals Altered Regulation of Cytoskeleton and Other ALS-Linked Proteins via 3′UTR Binding

By taking advantage of a human induced pluripotent stem cell-based model, scientists aimed to gain insights on the impact of amyotrophic lateral sclerosis (ALS) mutant FUS on the motoneuron proteome.
[Scientific Reports]
Garone, M. G., Alfano, V., Salvatori, B., Braccia, C., Peruzzi, G., Colantoni, A., Bozzoni, I., Armirotti, A., & Rosa, A. (2020). Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3′UTR binding. Scientific Reports, 10(1), 11827. https://doi.org/10.1038/s41598-020-68794-6 Cite
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