Tag results:

astrocytes

Exposure to Cadmium Induces Neuroinflammation and Impairs Ciliogenesis in hESC-Derived 3D Cerebral Organoids

[Science of the Total Environment] The authors identified that cadmium exposure specifically induced apoptosis in neurons and inhibited the proliferation of neural progenitor cells, but neural differentiation was not significantly affected in cerebral organoids.

Repopulation of Decellularized Retinas with hiPSC-Derived Retinal Pigment Epithelial and Ocular Progenitor Cells Shows Cell Engraftment, Organization and Differentiation

[Biomaterials] Mouse and porcine retinas were decellularized and the protein profile analyzed. Acellular retinal extracellular matrix scaffolds were then repopulated with human iPSC-derived retinal pigment epithelial cells or ocular progenitor cells to assess their integration, proliferation and organization.

Functional Immune Cell-Astrocyte Interactions

[Journal of Experimental Medicine] Scientists review the interactions between immune cells and astrocytes and their roles in health and neurological diseases, with a special focus on multiple sclerosis.

An Implantable Human Stem Cell-Derived Tissue-Engineered Rostral Migratory Stream for Directed Neuronal Replacement

[Communications Biology] The authors demonstrated that astrocyte-like-cells could be derived from adult human gingiva mesenchymal stem cells and used for Tissue-Engineered-rostral migratory stream fabrication.

Tunneling Nanotubes, TNT, Communicate Glioblastoma with Surrounding Non-Tumor Astrocytes to Adapt Them to Hypoxic and Metabolic Tumor Conditions

[Scientific Reports] Scientists demonstrated that tunneling nanotubes structures were induced between glioblastoma cells and surrounding non-tumor astrocytes to transfer tumor-derived mitochondria.

Astrocytic Interleukin-3 Programs Microglia and Limits Alzheimer’s Disease

[Nature] Astrocytes produced IL-3, which elicited transcriptional, morphological, and functional programming of microglia to endow them with an acute immune response program, enhanced motility, and the capacity to cluster and clear aggregates of Aβ and tau.

Popular