astrocytes

[Molecular Therapy-Methods & Clinical Development] Researchers tested the in vitro neuroprotective potential of mouse adipose derived stem cells in astrocyte/motor neuron co-cultures where amyotrophic lateral sclerosis (ALS) astrocytes show neurotoxicity.

[iScience] Single-cell transcriptomics of retinal cells, showed that fibroblast growth factor 21 (FGF21) receptor Fgfr1 was specifically expressed in Müller glia/astrocytes.

[Stem Cells] Scientists summarize the efforts to accomplish vascularization and perfusion of brain organoids, and they discuss these attempts from a forward‐looking perspective.

[Nature Metabolism] The authors showed that aldehyde dehydrogenase 2 (ALDH2) was expressed in astrocytes in the mouse cerebellum and that ethanol metabolism by astrocytic ALDH2 mediated behavioral effects associated with ethanol intoxication.

[Autophagy] The authors showed elevated activation of the MTOR pathway in human-derived astrocytes harboring mutant SOD1, which resulted in inhibition of macroautophagy/autophagy, increased cell proliferation, and enhanced astrocyte reactivity.

[Proceedings of the National Academy of Sciences of the United States of America] Researchers showed that glial fibrillary acidic protein (GFAP) was readily palmitoylated in vitro and in vivo; specifically, cysteine-291 was the unique palmitoylated residue in GFAP.