Researchers tested the in vitro neuroprotective potential of mouse adipose derived stem cells in astrocyte/motor neuron co-cultures where amyotrophic lateral sclerosis (ALS) astrocytes show neurotoxicity.
[Molecular Therapy-Methods & Clinical Development]
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Ciervo, Y., Gatto, N., Allen, C., Grierson, A., Ferraiuolo, L., Mead, R. J., & Shaw, P. J. (2021). Adipose derived stem cells protect motor neurons and reduce glial activation in both in vitro and in vivo models of ALS. Molecular Therapy - Methods & Clinical Development, 0(0). https://doi.org/10.1016/j.omtm.2021.03.017 Cite