Aspiration-Assisted Bioprinting of the Osteochondral Interface

Tissue spheroids, made of human adipose-derived stem cells, were differentiated in three dimensions into chondrogenic and osteogenic spheroids, which were confirmed by immunostaining and histology qualitatively, and biochemistry assays and gene expression, quantitatively.
[Scientific Reports]
Ayan, B., Wu, Y., Karuppagounder, V., Kamal, F., & Ozbolat, I. T. (2020). Aspiration-assisted bioprinting of the osteochondral interface. Scientific Reports, 10(1), 13148. https://doi.org/10.1038/s41598-020-69960-6 Cite
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Activating PIK3CA Mutation Promotes Adipogenesis of Adipose-Derived Stem Cells in Macrodactyly via Up-Regulation of E2F1

PIK3CA (H1047R) Activating Mutation and Enhanced Activity of PI3K/AKT Pathway were Detected in Macrodactylous Adipose-Derived Stem Cells (Mac-ADSCs).
[Cell Death & Disease]
Sun, B., Jiang, Y., Cui, H., Fang, X., Han, G., Dai, X., Zhou, S., Mao, H., & Wang, B. (2020). Activating PIK3CA mutation promotes adipogenesis of adipose-derived stem cells in macrodactyly via up-regulation of E2F1. Cell Death & Disease, 11(7), 1–11. https://doi.org/10.1038/s41419-020-02806-1 Cite
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Extracellular Vesicle‐Enclosed MiR‐486‐5p Mediates Wound Healing with Adipose‐Derived Stem Cells by Promoting Angiogenesis

Researchers investigated the role of adipose‐derived stem cells‐extracellular vesicles in the cutaneous wound healing accompanied with the study on the specific cargo‐medicated effects on wound healing.
[Journal of Cellular and Molecular Medicine]
Lu, Y., Wen, H., Huang, J., Liao, P., Liao, H., Tu, J., & Zeng, Y. (n.d.). Extracellular vesicle-enclosed miR-486-5p mediates wound healing with adipose-derived stem cells by promoting angiogenesis. Journal of Cellular and Molecular Medicine, n/a(n/a). https://doi.org/10.1111/jcmm.15387 Cite
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Adipose Stem Cells from Type 2 Diabetic Mice Exhibit Therapeutic Potential in Wound Healing

This study compared the phenotypes of adipose tissue-derived mesenchymal stem cells harvested from high-fat diet, streptozotocin-induced type 2 diabetes (T2D) and healthy Chow diet-fed C57BL/6 mice in vitro and their therapeutic effects for the treatment of wound healing in a mouse model of T2D.
[Stem Cell Research & Therapy]
Adipose stem cells from type 2 diabetic mice exhibit therapeutic potential in wound healing | Stem Cell Research & Therapy | Full Text. (n.d.). Retrieved July 20, 2020, from https://stemcellres.biomedcentral.com/articles/10.1186/s13287-020-01817-1 Cite
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Adipose Tissue: A Source of Stem Cells with Potential for Regenerative Therapies for Wound Healing

This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue as well as discussing the properties of adipose-derived stem cells and their promising applications for tissue engineering, scarring, and wound healing.
[Journal of Clinical Medicine]
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Self-Assembled Cell Sheets Composed of Mesenchymal Stem Cells and Gelatin Nanofibers for the Treatment of Full-Thickness Wounds

Dorsal wounds transplanted with the cell sheets exhibited higher wound-healing rates when a high concentration of gelatin was immobilized on the surfaces of the nanofibrils.
[Biomaterials Science]
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