Tissue spheroids, made of human adipose-derived stem cells, were differentiated in three dimensions into chondrogenic and osteogenic spheroids, which were confirmed by immunostaining and histology qualitatively, and biochemistry assays and gene expression, quantitatively.
PIK3CA (H1047R) Activating Mutation and Enhanced Activity of PI3K/AKT Pathway were Detected in Macrodactylous Adipose-Derived Stem Cells (Mac-ADSCs).
[Cell Death & Disease]
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Researchers investigated the role of adipose‐derived stem cells‐extracellular vesicles in the cutaneous wound healing accompanied with the study on the specific cargo‐medicated effects on wound healing.
[Journal of Cellular and Molecular Medicine]
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This study compared the phenotypes of adipose tissue-derived mesenchymal stem cells harvested from high-fat diet, streptozotocin-induced type 2 diabetes (T2D) and healthy Chow diet-fed C57BL/6 mice in vitro and their therapeutic effects for the treatment of wound healing in a mouse model of T2D.
[Stem Cell Research & Therapy]
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Adipose stem cells from type 2 diabetic mice exhibit therapeutic potential in wound healing | Stem Cell Research & Therapy | Full Text. (n.d.). Retrieved July 20, 2020, from https://stemcellres.biomedcentral.com/articles/10.1186/s13287-020-01817-1 Cite
This review describes the current understanding of the origin, different types, anatomical location, and genetics of adipose tissue as well as discussing the properties of adipose-derived stem cells and their promising applications for tissue engineering, scarring, and wound healing.
[Journal of Clinical Medicine]
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Dorsal wounds transplanted with the cell sheets exhibited higher wound-healing rates when a high concentration of gelatin was immobilized on the surfaces of the nanofibrils.
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