Stem Cell Differentiation with Consistent Lineage Commitment Induced by a Flash of Ultrafast-Laser Activation In Vitro and In Vivo

Researchers reported a non-invasive all-optical strategy to induce stem cell differentiation in vitro and in vivo that activated individual target stem cells in situ by delivering a transient 100-ms irradiation of a tightly focused femtosecond laser to a submicron cytoplasmic region of primary adipose-derived stem cells.